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Perricone MD High Potency Retinol Recovery Overnight Moisturizer is a nourishing moisturizer that works overnight with retinol to help improve the appearance of lines and wrinkles. It delivers hydration to replenish skin for the look of a smoother, more radiant complexion. How do I use it: Massage onto cleansed face and neck in the evening using a gentle upward motion. For best results, apply after your favorite Perricone MD serum, serum concentrate, or facial cream. From Perricone MD. Includes: